Structural bioinformatics incorporated intoARP/wARPmodel building

Structural bioinformatics

Motivation: Protein-protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low stability and difficulty to produce the proteins and assemble them in native conformation. Thus, docking algorithms have been developed to provide an in silico approach of the problem. A protein-protein docking procedure ...

Bioinformatics III: Structural Bioinformatics and Genome Analysis

Bioinformatics in structural genomics.

Engineering bioinformatics: building reliability, performance and productivity into bioinformatics software

There is a lack of software engineering skills in bioinformatic contexts. We discuss the consequences of this lack, examine existing explanations and remedies to the problem, point out their shortcomings, and propose alternatives. Previous analyses of the problem have tended to treat the use of software in scientific contexts as categorically different from the general application of software e...

Structural Bioinformatics for Protein Engineering